Pinus koraiensis seed oil (PinnoThin TM ) supplementation reduces body weight gain and lipid concentration in liver and plasma of mice

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About the Journal Editorial Office Editorial Board Copy right and self-archiving policy Peer review process Instructions for Reviewers Printed version subscription Abstracting and indexing Contact

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Policies General information Open Access, Licensing terms, Commercial use and Copyright terms policies Self-archiving policy and Archive policies Article Correction and Withdrawal policy Manuscript Submission policy Authorship policy Conflict of Interest policy Language considerations policy Plagiarism and Duplicate publications policy Ethics policy Review process policy Acceptance of manuscripts policy Online First Articles and Special Issues policies Generative artificial intelligence (AI) policy Advertising policy

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ORIGINAL PAPER

Pinus koraiensis seed oil (PinnoThin^TM) supplementation reduces body weight gain and lipid concentration in liver and plasma of mice

A. Ferramosca ¹

,

V. Savy ¹

,

A. W. C. Einerhand ²

,

V. Zara ¹

1

Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Via Prov.le Lecce-Monteroni, I-73100 Lecce, Italy

2

Lipid Nutrition BV, PO Box 4, 1520 AA Wormerveer, The Netherlands

Publication date: 2008-10-27

Corresponding author

V. Zara

Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Via Prov.le Lecce-Monteroni, I-73100 Lecce, Italy

J. Anim. Feed Sci. 2008;17(4):621-630

DOI: https://doi.org/10.22358/jafs/66690/2008

KEYWORDS

fatty acid synthesis

pine nut oil (PinnoThinTM)

ABSTRACT

Pinus koraiensis seed oil (pine nut oil), containing pinolenic acid, has been proposed as a beneficial fat by virtue of its effects on some lipid variables. In this study the effects of a pine nut oil-supplemented diet in mice, in comparison to control animals fed with a maize oil enriched diet, were investigated. Pine nut oil caused a significant reduction in body weight gain and liver weight (37.4 and 13.7%, respectively). An impressive decrease in plasma triglycerides and total cholesterol (31.8 and 28.5%, respectively) was also found in pine nut oil-fed animals. Liver lipids were also positively influenced by pine nut oil. The mitochondrial and cytosolic enzyme activities involved in hepatic fatty acid synthesis were strongly reduced both in pine nut oil and maize oil-fed animals, thus suggesting that the beneficial effects of pine nut oil are not due to an inhibition of hepatic lipogenesis.

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