ORIGINAL PAPER
Can silver nanoparticles affect the mineral content,
structure and mechanical properties of chicken
embryo bones?
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1
Warsaw University of Life Sciences,
Department of Animal Nutrition and Feed Science, Ciszewskiego 8, 02-786 Warsaw, Poland
2
Warsaw University of Life Sciences,
Faculty of Veterinary Medicine, Department of Morphologic Sciences, Ciszewskiego 8, 02-786 Warsaw, Poland
3
University of Copenhagen, Department of Basic Animal and Veterinary Sciences,
Groennegaardsvej 3, 1870 Frederiksberg C, Denmark
Publication date: 2010-05-09
Corresponding author
J. Sikorska
Warsaw University of Life Sciences,
Department of Animal Nutrition and Feed Science, Ciszewskiego 8, 02-786 Warsaw, Poland
J. Anim. Feed Sci. 2010;19(2):286-291
KEYWORDS
ABSTRACT
Biomedical application of silver nanoparticles has recently gained much attention. In this study,
we investigated whether hydrocolloids of silver nanoparticles (nano-Ag) are deposited in chicken
bones during embryogenesis and to what extent they can affect biochemical characteristics, mineral
content, structure, and mechanical properties of bones. Hydrocolloids (0.3 ml), containing 50 ppm
of nano-Ag, were injected in ovo prior to incubation of eggs. After 20 days of incubation, blood
and thigh bones were isolated and analysed. Nano-Ag was deposited in embryo thigh bones, but
did not affect the structure or mechanical properties of the bone. There was no effect of nano-Ag
on the selected biochemical indices, but there was a tendency towards increasing mineral content,
indicating that nanoparticles may influence bone mineralization. Considering that nano-Ag is
absorbed by the embryo skeleton without affecting bone properties, these particles might be a good
candidate for carriers of micronutrients or drugs into bones.
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