Buprenorphine was given intravenously to goats to study if it dampens pain and the increase
in plasma vasopressin concentration during labour. Seven goats were given buprenorphine (0.005
mg/kg) and 6 goats were given saline. The expressions of pain were evaluated on a Visual Analogue
Scale from 0- 10 (mild to severe pain) and the vasopressin concentration was measured with a
radioimmunoassay. The pain expressions did not differ between the goats that received the drug
and the controls. However, the expressions of pain were correlated to the vasopressin concentration,
giving support to the idea that the vasopressin concentration is affected by pain.
CITATIONS(3):
1.
Parturition progress and behaviours in dairy cows with calving difficulty Alice C. Barrier, Marie J. Haskell, Alastair I. Macrae, Cathy M. Dwyer Applied Animal Behaviour Science
Clinical pharmacology of buprenorphine in healthy, lactating goats C. INGVAST-LARSSON, K. SVARTBERG, E. HYDBRING-SANDBERG, U. BONDESSON, K. OLSSON Journal of Veterinary Pharmacology and Therapeutics
Effect of a difficult calving on the vigour of the calf, the onset of maternal behaviour, and some behavioural indicators of pain in the dam A.C. Barrier, E. Ruelle, M.J. Haskell, C.M. Dwyer Preventive Veterinary Medicine
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