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ORIGINAL PAPER
Effect of single nucleotide polymorphisms in the UCP3 and FOXO1
genes on carcass quality traits in Qinchuan cattle
1
Qinghai University, State Key Laboratory of Plateau Ecology and Agriculture, Xining, 810016 Qinghai Province, People’s Republic of China
2
Qinghai University, College of Agriculture and Animal Husbandry, Xining, 810016 Qinghai Province, People’s Republic of China
Publication date: 2018-11-28
Corresponding author
J. L. Jia
Qinghai University, College of Agriculture and Animal Husbandry, Xining, 810016 Qinghai Province, People’s Republic of China
Qinghai University, College of Agriculture and Animal Husbandry, Xining, 810016 Qinghai Province, People’s Republic of China
J. Anim. Feed Sci. 2018;27(4):301-306
KEYWORDS
TOPICS
ABSTRACT
Allelic and genotypic distributions of polymorphisms in the uncoupling
protein 3 (UCP3) and forkhead box O1 (FOXO1) genes were assessed in 491 Chinese Qinchuan cattle. Single-locus genotype effects and the combined
effect of polymorphisms within those two genes were probed to determine
possible association with the carcass quality traits. Using DNA sequencing, in total
three novel single nucleotide polymorphisms (SNPs) were identified, including
a SNP in the intron 1 of UCP3 (NC_037339.1: g.6821C>T), and two SNPs within
the 3’UTR of FOXO1 (NC_037342.1: g.93063G>A and g.93280A>G). Statistical
analyses indicated that the g.6821C>T (UCP3) and g.93280A>G (FOXO1)
polymorphisms were significantly associated with intramuscular fat content
(P < 0.05 or P < 0.01). So, the results obtained in this study constitute a valuable
information about the markers applicable in marker-assisted selection (MAS)
used in improving carcass quality traits.
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