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ORIGINAL PAPER
Effects of different combinations of dietary starch and non-starch polysaccharides on intestinal functions,
and lipid and glucose metabolism in weaned pigs
1
Sichuan Agricultural University, Institute of Animal Nutrition, Key Laboratory for Animal Disease-Resistance Nutrition of Ministry of Education, Chengdu, Sichuan 611130, China
Publication date: 2020-09-30
Corresponding author
B. Yu
Sichuan Agricultural University, Institute of Animal Nutrition, Key Laboratory for Animal Disease-Resistance Nutrition of Ministry of Education, Chengdu, Sichuan 611130, China
Sichuan Agricultural University, Institute of Animal Nutrition, Key Laboratory for Animal Disease-Resistance Nutrition of Ministry of Education, Chengdu, Sichuan 611130, China
J. Anim. Feed Sci. 2020;29(3):241-249
KEYWORDS
TOPICS
ABSTRACT
The aim of the present study was to investigate the effects of different combinations of dietary starch and non-starch polysaccharides (NSP) on intestinal functions, and lipid and glucose metabolism in pigs. Fifty-four weaned pigs weighing 6.71 ± 0.52 kg were randomly assigned according to body weight and sex to 3 treatments with 6 replicates per treatment and 3 pigs
per replicate, and were fed: T1 diet containing starch with amylose/amylopectin (AM/AP) ratio of 1:1 and NSP 3% (a mixture of inulin and cellulose in a ratio 1:1), T2 diet with starch of AM/AP ratio 2:1 and NSP 1% or T3 diet containing starch with AM/AP ratio of 1:2 and NSP 2%. Pigs were fed experimental diets for 28 days. It was shown that in animals fed T1 diet mRNA expression of glucagonlike peptide-2, zonula occludens 1 and occludin (P < 0.05) were up-regulated and tended to be increased the mRNA level of insulin-like growth factor-1 (P = 0.06) in colon, the activity of lactase in jejunum was increased (P < 0.05), mRNA expression of insulin receptor substrate 1 and glucose-6-phosphatase in liver were improved (P < 0.05), and the activity of lipoprotein lipase (P < 0.05) was decreased and the activity of malate dehydrogenase tended to be enhanced (P = 0.07) in longissimus dorsi muscle. Feeding T1 diet promoted the intestinal functions and improved to some extent lipid and glucose metabolism in pigs. So, carbohydrates combination of starch with AM/AP ratio of 1:1 and NSP 3% can be recommended for weaned pigs.
ACKNOWLEDGEMENTS
This study was supported by National Natural Science Foundation of China (31730091) and the
National Key Research and Development Program of China (2017YFD0500503).
REFERENCES (49)
1.
AOAC International, 1995. Official Methods of Analysis of AOAC International. 16th Edition. Arlington, VA (USA).
2.
Aumiller T., Mosenthin R., Weiss E., 2015. Potential of cereal grains and grain legumes in modulating pigs’ intestinal microbiota - A review. Livest. Sci. 172, 16–32, https://doi.org/10.1016/j.livs....
3.
Bach Knudsen K.E., 2011. Triennial Growth Symposium: Effects of polymeric carbohydrates on growth and development in pigs. J. Anim. Sci. 89, 1965–1980, https://doi.org/10.2527/jas.20....
4.
Behall K.M., Scholfield D.J., 2005. Food amylose content affects post¬prandial glucose and insulin responses. Cereal Chem. 82, 654–659, https://doi.org/10.1094/CC-82-....
5.
Bloemen J.G., Olde Damink S.W.M., Venema K., Buurman W.A., Jalan R., Dejong C.H.C., 2010. Short chain fatty acids exchange: Is the cirrhotic, dysfunctional liver still able to clear them? Clin. Nutr. 29, 365–369, https://doi.org/10.1016/j.clnu....
6.
Bloom S.R., Polak J.M., 1982. The hormonal pattern of intestinal adaptation. A major role for enteroglucagon. Scand. J. Gastroenterol. Suppl. 74, 93–103.
7.
Bosaeus I., 2004. Fibre effects on intestinal functions (diarrhoea, constipation and irritable bowel syndrome). Clin. Nutr. Suppl. 1, 33–38, https://doi.org/10.1016/j.clnu....
8.
Campbell J., Crenshaw J., Polo J., 2013. The biological stress of early weaned piglets. J. Anim. Sci. Biotechnol. 2, 45–48, https://doi. org/ https://doi.org/10.1186/2049-1....
9.
Chen H., Mao X.B., He J., Huang Z., Yu J., Zheng P., Chen D., 2013. Dietary fibre affects intestinal mucosal barrier function and regulates intestinal bacteria in weaning piglets. Br. J. Nutr. 110, 1837–1848, https://doi.org/10.1017/S00071....
10.
Chen H., Mao X.B., Yin J., He J., Huang Z., Zheng P., Chen D., 2015. Comparison of jejunal digestive enzyme activities, expres-sion of nutrient transporter genes, and apparent fecal di¬gestibility in weaned piglets fed diets with varied sources of fiber. J. Anim. Feed Sci. 24, 41–47, https://doi.org/10.22358/jafs/....
11.
Chen J., Li Y., Yu B., Chen D.W., Mao X.B., Zheng P., Luo J.Q., He J., 2018. Dietary chlorogenic acid improves growth performance of weaned pigs through maintaining antioxidant capacity and intestinal digestion and absorption function. J. Anim. Sci. 96, 1108–1118, https://doi.org/10.1093/jas/sk....
12.
Chen T.T., Chen D.W., Tian G. et al., 2019. Effects of soluble and in¬soluble dietary fiber supplementation on growth performance, nutrient digestibility, intestinal microbe and barrier function in weaning piglet. Anim. Feed. Sci. Technol. 260, 114335, https://doi.org/10.1016/j.anif....
13.
Chou J.Y., Mansfield B.C., 2010. Mutations in the glucose-6-phosphatase-alpha (G6PC) gene that cause type Ia glycogen storage disease. Hum. Mutat. 29, 921–930, https://doi.org/10.1002/humu.2....
14.
de Lange C.F.M., Pluske J., Gong J., Nyachoti C.M., 2010. Strategic use of feed ingredients and feed additives to stimulate gut health and development in young pigs. Livest. Sci. 134, 124–134, https://doi.org/10.1016/j.livs....
15.
De Vadder F., Kovatcheva-Datchary P., Goncalves D. et al., 2014. Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits. Cell 156, 84–96, https://doi.org/10.1016/j.cell....
16.
den Besten G., Lange K., Havinga R. et al., 2013. Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids. Am. J. Physiol. Gastrointest. Liver. Physiol. 305, G900–G910, https://doi.org/10.1152/ajpgi.....
17.
Diao H., Jiao A., Yu B., Mao X., Chen D.W., 2019. Gastric infusion of short-chain fatty acids can improve intestinal barrier function in weaned piglets. Genes. Nutr. 14, 3–16, https://doi.org/10.1186/s12263....
18.
Donnelly K.L., Smith C.I., Schwarzenberg S.J., Jessurun J., Boldt M.D., Parks E.J., 2005. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 115, 1343–1351, https://doi.org/10.1172/JCI236....
19.
Flint H.J., Scott K.P., Louis P., Duncan S.H., 2012. The role of the gut microbiota in nutrition and health. Nat. Rev. Gastroenterol. Hepatol. 9, 577–589, https://doi.org/10.1038/nrgast....
20.
Fritsche L., Weigert C., Haring H.U., Lehmann R., 2008. How insulin receptor substrate proteins regulate the metabolic capacity of the liver implications for health and disease. Curr. Med. Chem. 15, 1316–1329, https://doi.org/10.2174/092986....
21.
Han G.Q., Xiang Z.T., Yu B., Chen D.W., Qi H.W., Mao X.B., Chen H., Mao Q., Huang Z.Q., 2012. Effects of different starch sources on Bacillus.spp. in intestinal tract and expression of intestinal development related genes of weanling piglets. Mol. Biol. Rep. 39, 1869–1876, https://doi.org/10.1007/s11033....
22.
Han H., Zhang K., Ding X., Bai S., Luo Y., Wang J., Peng H., Zeng Q., 2016. Effects of dietary nanocrystalline cellulose supplementation on growth performance, carcass traits, intestinal development and lipid metabolism of meat ducks. Anim. Nutr. 2, 192–197, https://doi.org/10.1016/j.anin....
23.
He J., Chen D., Yu B., 2010. Metabolic and transcriptomic responses of weaned pigs induced by different dietary amylose and amylopectin ratio. PLoS ONE. 5, e15110, https://doi.org/10.1371/journa....
24.
Ichimura A., Hirasawa A., Hara T., Tsujimoto G., 2009. Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis. Prostaglandins Other Lipid. Mediat. 89, 82–88, https://doi.org/10.1016/j.pros....
25.
Jha R., Berrocoso J.D., 2015. Review: Dietary fiber utilization and its effects on physiological functions and gut health of swine. Animal 9, 1441–1452, https://doi.org/10.1017/S17517....
26.
Kim J.C., Hansen C., Mullan B., Pluske J., 2012. Nutrition and pathology of weaner pigs: Nutritional strategies to support barrier function in the gastrointestinal tract. Anim. Feed. Sci. Technol. 173, 3–16, https://doi.org/10.1016/j.anif....
27.
Kumar V., Sinha A.K., Makkar H.P.S., de Boeck G., Becker K., 2012. Dietary roles of non-starch polysachharides in human nutrition: A Review. Crit. Rev. Food. Sci. Nutr. 52, 899–935, https://doi.org/10.1080/104083....
28.
Li Y.J., Li J.L., Zhang L., Gao F., 2017. Effects of dietary starch types on growth performance, meat quality and myo-fibre type of finishing pigs. Meat Sci. 131, 60–67, https://doi.org/10.1016/j.meat....
29.
Lin H.V., Frassetto A., Kowalik E.J. et al., 2012. Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. PloS ONE 7, e35240, https://doi.org/10.1371/journa....
30.
Lindberg J.E., 2014 Fiber effects in nutrition and gut health in pigs. J. Anim. Sci. Biotechnol. 5, 273–279, https://doi.org/10.1186/2049-1....
31.
Louis P., Flint H.J., 2017. Formation of propionate and butyrate by the human colonic microbiota. Environ. Microbiol. 19, 29–41, https://doi.org/10.1111/1462-2....
32.
Mead J.R., Irvine S., Ramji D., 2003. Lipoprotein lipase: Structure, function, regulation, and role in disease. J. Mol. Med. (Ber) 80, 753–769, https://doi.org/10.1007/s00109....
33.
Mohamed A.B., Rémond D., Chambon C., et al., 2019. A mix of dietary fermentable fibers improves lipids handling by the liver of overfed minipigs. J. Nutr. Biochem. 65, 72–82, https://doi.org/10.1016/j.jnut....
34.
Morrison D.J., Preston T., 2016. Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism. Gut Microbes 7, 1–12, https://doi.org/10.1080/194909....
35.
NRC (National Research Council), 2012. Nutrient Requirements of Swine. 11th Revised Edition. The National Academies Press. Washington, DC (USA), https://doi.org/10.17226/13298.
36.
Pfaffl M.W., 2001. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, 900–905, https://doi.org/10.1093/nar/29....
37.
Regmi P.R., Matte J.J., Ganzle M.G., van Kempen T.A., Zijlstra R.T., 2010. Starch chemistry affects kinetics of glucose absorption and insulin response in swine. Livest. Sci. 134, 44–46, https://doi.org/10.1016/j.livs....
38.
Regmi P.R., Metzler-Zebeli B.U., Ganzle M.G., van Kempen T.A., Zijlstra R.T., 2011. Starch with high amylose content and low in vitro digestibility increases intestinal nutrient flow and microbial fermentation and selectively promotes bifidobacteria in pigs. J. Nutr. 141, 1273–1280, https://doi.org/10.3945/jn.111....
39.
Singh J., Dartois A., Kaur L., 2010. Starch digestibility in food matrix: a review. Trends Food Sci. Technol. 21, 168–180, https://doi.org/10.1016/j.tifs....
40.
Snel M., Jonker J.T., Schoones J., Lamb H., de Roos A., Pijl H., Smit J.W., Meinders A.E., Jazet I.M., 2012. Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions. Int. J. Endocrinol. 2012, 983–814, https://doi.org/10.1155/2012/9....
41.
Ulluwishewa D., Anderson R.C., Mcnabb W.C., Moughan P.J., Wells J.M., Roy N.C., 2011. Regulation of tight junction permeability by intestinal bacteria and dietary components. J. Nutr. 141, 769–776, https://doi.org/10.3945/jn.110....
42.
Wang H.J., Pu J.N., Chen D.W., Tian G., Mao X.B., 2019. Effects of dietary amylose and amylopectin ratio on growth performance, meat quality, postmortem glycolysis and muscle fibre type transformation of finishing pigs. Arch. Anim. Nutr. 73, 194–207, https://doi.org/10.1080/174503....
43.
Wenk C., 2001. The role of fiber in digestive physiology of the pig. Anim. Feed Sci. Technol. 90, 21–33, https://doi.org/10.1016/S0377-....
44.
Wong J.M., de Souza R., Kendall C.W., Emam A., Jenkins D.J., 2006. Colonic health: fermentation and short chain fatty acids. J. Clin. Gastroenterol. 40, 235–243, https://doi.org/10.1097/000048....
45.
Wu X., Chen D., Yu B., Luo Y., Zheng P., Mao X., Yu J., He J., 2018. Effect of different dietary non-starch fiber fractions on growth performance, nutrient digestibility, and intestinal development in weaned pigs. Nutrition 51–52, 20–28, https://doi.org/10.1016/j.nut.....
46.
Xiang Z.T., Qi H.W., Han G.Q. et al., 2011. Real-time TaqMan polymerase chain reaction to quantify the effects of different sources of dietary starch on Bifidobacterium in the intestinal tract of piglets. Afr. J. Biotechnol. 10, 5059–5067, https://doi.org/10.1186/1475-2....
47.
Xiao S., Li S., Zhang J. et al., 2009. Cloning and characterization of class 1 and class 2 insulin-like growth factor-I mRNA in Songliao black pig. Mol. Biol. Rep. 36, 415–421, https://doi.org/10.1007/s11033....
48.
Yang C., He J., Yu B., Yu J., Mao X.B., Chen D.W., Yin Y.L., 2018. The effect of dietary amylose/amylopectin ratio on serum and hepatic lipid content and its molecular mechanisms in growing-finishing pigs. J. Anim. Physiol. Anim. Nutr. 102, 1657–1665, https://doi.org/10.1111/jpn.12....
49.
Zhao L., Zhang F., Ding X. et al., 2018. Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes. Science 359, 1151–1156, https://doi.org/10.1126/scienc....
CITATIONS (1):
1.
Carbohydrates effects on nutrition and health functions in pigs
Hua Zhou, Bing Yu, Hong Chen, Daiwen Chen
Animal Science Journal
Hua Zhou, Bing Yu, Hong Chen, Daiwen Chen
Animal Science Journal
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