Effects of pentagastrin and IGF-1 on DNA synthesis
of rumen epithelial cells of dairy cow
and neonatal calf

Pentagastrin (PG) (10^-12, 10^-11, 10^-10and 10^-9 mol/L) and IGF-1 (25 and 50 µg/L) increased DNA synthesis of rumen epithelial cell (REC) of dairy cows in a dose dependent manner by approximately 30-40% and 13% (P<0.05), respectively. Proglumide (gastrin/CCK B receptor blocker) abolished the trophic action of PG, which indicates that the positive effect of PG on REC is probably mediated by the gastrin receptor. REC of neonatal calves did not response to PG. However, IGF-1, at all given doses (25-200 µg/L), promoted DNA synthesis in REC of neonatal calves (P<0.05).

CITATIONS (2):

Elevated cyclin D1 expression is governed by plasma IGF-1 through Ras/Raf/MEK/ERK pathway in rumen epithelium of goats supplying a high metabolizable energy diet
J. Lu, H. Zhao, J. Xu, L. Zhang, L. Yan, Z. Shen
Journal of Animal Physiology and Animal Nutrition

CrossRef

Establishment of Immortalized Yak Ruminal Epithelial Cell Lines by Lentivirus-Mediated SV40T and hTERT Gene Transduction
JunMei Wang, Rui Hu, Zhisheng Wang, Yixin Guo, Sen Wang, Huawei Zou, Quanhui Peng, Yahui Jiang, Kai Wang
Oxidative Medicine and Cellular Longevity

CrossRef

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1230-1388

Assigning DOI numbers, introducing articles from supplements and recent publications to POL-index database, maintaining anti-plagiarism detection, electronic system to proceed manuscripts and webpage of the Journal with interactive pdf files, and language correction of manuscripts published in Journal of Animal and Feed Sciences are financed in the years 2018–2019 by the Ministry of Science and Higher Education from the funds for science popularization activities, Agreement No. 631/P-DUN/2018.