Effects of polyunsaturated fatty acids on hepatic
PPARα mRNA levels in the transition cow

A total of 33 Holstein cows were fed one of three diets with different fatty acid composition: supplement with 85% saturated fatty acids (EB), supplement with 10% linseed (LI), and control with no added fat (CO). Blood and liver samples were collected on week -6, -2, +2, and +4 relative to calving. Two weeks after calving, liver PPARα mRNA levels were lower in cows fed EB compared to those that were fed CO. These results also showed that lower liver PPARα mRNA levels are associated with lower plasma glucose concentration in the overall cow population (n=33)

CITATIONS (7):

Expression of fibroblast growth factor 21 in the liver of dairy cows in the transition period and during lactation
G. Schlegel, R. Ringseis, J. Keller, F. J. Schwarz, W. Windisch, K. Eder
Journal of Animal Physiology and Animal Nutrition

CrossRef

Alterations in Hepatic FGF21, Co-Regulated Genes, and Upstream Metabolic Genes in Response to Nutrition, Ketosis and Inflammation in Peripartal Holstein Cows
Haji Akbar, Fernanda Batistel, James K. Drackley, Juan J. Loor, Wenke Feng
PLOS ONE

CrossRef

Comparison of hepatic adaptation in extreme metabolic phenotypes observed in early lactation dairy cows on-farm
H. A. van Dorland, M. Graber, S. Kohler, A. Steiner, R. M. Bruckmaier
Journal of Animal Physiology and Animal Nutrition

CrossRef

Overfeeding Dairy Cattle during Late-Pregnancy Alters Hepatic PPARα-Regulated Pathways Including Hepatokines: Impact on Metabolism and Peripheral Insulin Sensitivity
M. Jawad Khan, Carolina B. Jacometo, Daniel E. Graugnard, Marcio N. Corrêa, Eduardo Schmitt, Felipe Cardoso, Juan J. Loor
Gene Regulation and Systems Biology

CrossRef

Effects of Flaxseed on Protein Requirements and N Excretion of Dairy Cows Fed Diets with Two Protein Concentrations
H.V. Petit, M. Ivan, P.S. Mir
Journal of Dairy Science

CrossRef

Hepatic gene expression in multiparous Holstein cows treated with bovine somatotropin and fed n-3 fatty acids in early lactation
M. Carriquiry, W.J. Weber, S.C. Fahrenkrug, B.A. Crooker
Journal of Dairy Science

CrossRef

Expression of genes involved in hepatic carnitine synthesis and uptake in dairy cows in the transition period and at different stages of lactation
Gloria Schlegel, Janine Keller, Frank Hirche, Stefanie Geißler, Frieder Schwarz, Robert Ringseis, Gabriele Stangl, Klaus Eder
BMC Veterinary Research

CrossRef

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