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ORIGINAL PAPER
Effects of supplementation with Angelica sinensis Radix
and its powder formulation on growth performance, serum
antioxidant capacity, immune response and intestinal microflora
of broiler chickens
1
Gansu Academy of Sciences, Institute of Biology, Key Laboratory of Microbial Resources Exploitation
and Application of Gansu Province, Lanzhou 730000, China
Publication date: 2024-08-27
Corresponding author
Z. Y. Wang
Gansu Academy of Sciences, Institute of Biology, Key Laboratory of Microbial Resources Exploitation and Application of Gansu Province, Lanzhou 730000, China
Gansu Academy of Sciences, Institute of Biology, Key Laboratory of Microbial Resources Exploitation and Application of Gansu Province, Lanzhou 730000, China
J. Anim. Feed Sci. 2024;33(4):504-516
KEYWORDS
TOPICS
ABSTRACT
The objective of this study was to characterise the effects of supplementation
with Angelica sinensis Radix (ASR) powder and a preparation containing
ASR powder (Danggui Buxue Decoction, DBD) on growth performance,
antioxidant capacity, immune activity, and caecal bacterial microbiota in broiler
chickens. A total of 180 one-day-old male Luhua broiler chickens were randomly
assigned to three groups. Broiler chickens in the control group were fed a basal
diet, the ASR group was administered a basal diet supplemented with 1% ASR
powder, and the DBD group received a basal diet supplemented with 1% DBD
powder. Results showed significant increases in serum glutathione peroxidase
and catalase activities, as well as serum immunoglobulin A levels in both the
ASR and DBD groups compared to the control group (P < 0.05). Additionally,
the malondialdehyde content was significantly lower in the ASR group compared
to other groups (P < 0.05). Supplementation with ASR and DBD also had
notable effects on the composition of broiler intestinal microbiota, particularly
influencing the abundance of Firmicutes and Bacteroidetes, as demonstrated by
high-throughput sequencing analysis. These findings suggest that dietary ASR
and DBD supplementation enhanced antioxidant capacity, immune status, and
intestinal flora diversity in broiler chickens, indicating their potential as effective
phytogenic feed additives.
FUNDING
The presented work was financed by ‘Gansu Top Leading Talent Plan, 2021’ and ‘The Youth Fund of Gansu Academy of Sciences, grant number 2023QN-04’.
CONFLICT OF INTEREST
The Authors declare that there is no conflict of interest.
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