Enrichment of lamb rations with carnosic acid
and seleno-compounds affects the content
of selected lipids and tocopherols in the pancreas

The aim of this study was to evaluate changes in the content of fatty acids (FA), tocopherols, total cholesterol (T-Ch) and malondialdehyde (MDA) in the pancreas of lambs fed supplemented diets. Corriedale lambs were fed a diet with 2% rapeseed oil (RO) and 1% fish oil (FO) (control diet) or experimental diets with the addition of 2% RO, 1% FO, 0.1% carnosic acid (CAc) (CAc diet) and 0.35 ppm Se in the form of selenized yeast (SeYe) (CAcSeYe diet) or selenate (SeVI) (CAcSeVI diet). An increase in the content of total saturated FA (SFA), thrombogenic SFA and all FA was observed in the pancreas of lambs fed the CAc diet compared to control and CAcSeYe diets. All experimental diets increased the ratio of monounsaturated FA (ΣMUFA) to ΣFA and desaturation indices in the pancreas compared to the control diet. Conjugated linoleic acid isomer contents and the hypocholesterolemic/hypercholesterolemic FA ratio in the pancreas of lambs fed all experimental diets was higher than in those fed the control diet. The CAcSeVI diet decreased the content of T-Ch in the pancreas compared to the control, CAc and CAcSeYe diets. Lambs fed the CAc diet had a higher content of tocopherols in the pancreas than the lambs fed the control, CAcSeYe and CAcSeVI diets. The CAcSeVI diets decreased the content of T-Ch and tocopherols in the pancreas compared to the CAcSeYe diet. The CAc diet increased modified PUFA peroxidation indices in the pancreas compared to the control, CAcSeYe and CAcSeVI diets.

FUNDING

This study was in part supported by the National Science Centre (Grant No. 2013/09/B/NZ9/00291) and by the statutory funds from The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences (Poland).

CONFLICT OF INTEREST

The Authors declare that there is no conflict of interest.

METADATA IN OTHER LANGUAGES:

Chinese

羔羊日粮中添加鼠尾草酸和硒化合物对胰腺中特定脂质和生育酚含量的影响

摘要：本研究的目的是评估日粮补充鼠尾草酸和硒化合物对羔羊胰腺中脂肪酸（FA）、生育酚、总胆固醇（T-Ch）和丙二醛（MDA）含量的变化。将考力代羔羊分为四组，对照组（Control组）：含2%菜籽油（RO）和1%鱼油（FO）的基础日粮，试验组分为，CAc组：添加2%RO、1%FO和0.1%鼠尾草酸（CAc）、CAcSeYe 组：添加硒化酵母（SeYe）形式的硒 0.35ppm 和CAcSeVI组：添加硒酸盐（SeVI）。与对照组和CAcSeYe组相比，CAc组羔羊胰腺中观察到总饱和脂肪酸（SFA）、致血栓饱和脂肪酸和总脂肪酸的含量增加。所有试验日粮组都增加了羔羊胰腺中总单不饱和脂肪酸和总脂肪酸的比率（ΣMUFA/ΣFA）和去饱和指数。所有试验日粮组羔羊胰腺中共轭亚油酸异构体含量和低胆固醇血症/高低胆固醇血症脂肪酸比值均高于对照组羔羊。与对照组、CAc和CAcSeYe相比，CAcSeVI组羔羊胰腺中T-Ch的含量降低。CAc组羔羊胰腺中生育酚的含量高于对照组、CAcSeYe和CAcSeVI组羔羊。与CAcSeYe组相比，CAcSeVI组羔羊胰腺中T-Ch和生育酚含量降低。与对照组、CAcSeYe组和CAcSeVI组羔羊相比，CAc组羔羊胰腺中的改良多不饱和脂肪酸的过氧化指数增加。

REFERENCES (56)

Acosta-Montaño P., García-González V., 2018. Effects of dietary fatty acids in pancreatic beta cell metabolism, implications in homeostasis. Nutrients 10(4), 393, https://doi.org/10.3390/nu1004....