SHORT COMMUNICATION
Exogenous leptin does not affect exocrine
pancreatic secretion in conscious sheep
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1
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland
2
Department of Physiology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, 069-8501 Hokkaido, Japan
Publication date: 2004-08-30
Corresponding author
W. Korczyński
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland
J. Anim. Feed Sci. 2004;13(Suppl. 1):425-428
KEYWORDS
ABSTRACT
The experiment was performed on 10 Black Suffolk sheep of 59±8 kg BW. The animals were
equipped with two catheters in common bile duct and one in duodenum and set of three bipolar
electrodes sutured on the duodenum. In accordance to duodenal electromyography activity, effect of
exogenous leptin on pancreatic juice secretion was studied. Administration of leptin (2-10 μg kg-1
BW intravenously) did not affect the volume, protein, amylase and bicarbonates output in pancreatic
juice. In conclusion, the results suggest, that in the doses used, leptin have no effect on pancreatic
secretion.