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REVIEW PAPER
How does bacterial endotoxin influence gonadoliberin/gonadotropins secretion and action?
1
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences,
Instytucka 3, 05-110 Jabłonna, Poland
Publication date: 2016-11-25
Corresponding author
D. Tomaszewska-Zaremba
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland
J. Anim. Feed Sci. 2016;25(4):283-291
KEYWORDS
ABSTRACT
This review summarizes data concerning the mechanisms by which
bacterial endotoxin, lipopolysaccharide (LPS), inhibits gonadoliberin (GnRH)/
luteinizing hormone (LH) secretion in mammals. LPS is a major component of
Gram-negative bacteria cell walls and is released from the surface of replicated
and dying Gram-negative bacteria into circulation. LPS is commonly used to
induce immune/inflammatory challenge in animals. In this article the site of
endotoxin action as well as LPS induced mediators are discussed. Hypothalamus
seems to be a place where majority of the immune-neuroendocrine interactions
occur, however the results of many research suggest that LPS may interfere
with reproductive system at the pituitary level as well. Endotoxin may affect
GnRH/LH secretion directly via toll-like receptors (TLR)4/TLR2 located both in
the hypothalamus and pituitary or indirectly through the intermediates such as
cytokines, catecholamines, prostaglandins or opioids.
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CITATIONS (8):
1.
Peripheral Inhibitor of AChE, Neostigmine, Prevents the Inflammatory Dependent Suppression of GnRH/LH Secretion during the Follicular Phase of the Estrous Cycle
Andrzej P. Herman, Janina Skipor, Agata Krawczyńska, Joanna Bochenek, Karolina Wojtulewicz, Hanna Antushevich, Anna Herman, Kamila Paczesna, Katarzyna Romanowicz, Dorota Tomaszewska-Zaremba
BioMed Research International
Andrzej P. Herman, Janina Skipor, Agata Krawczyńska, Joanna Bochenek, Karolina Wojtulewicz, Hanna Antushevich, Anna Herman, Kamila Paczesna, Katarzyna Romanowicz, Dorota Tomaszewska-Zaremba
BioMed Research International
2.
The effect of inflammation on the synthesis of luteinizing hormone and GnRH receptor expression in the pars tuberalis of ewe during different photoperiodic conditions
Karolina Wojtulewicz, Dorota Tomaszewska-Zaremba, Agata Krawczyńska, Monika Tomczyk, Andrzej Przemysław Herman
Canadian Journal of Animal Science
Karolina Wojtulewicz, Dorota Tomaszewska-Zaremba, Agata Krawczyńska, Monika Tomczyk, Andrzej Przemysław Herman
Canadian Journal of Animal Science
3.
Effect of CD14/TLR4 antagonist on GnRH/LH secretion in ewe during central inflammation induced by intracerebroventricular administration of LPS
Karolina Haziak, Andrzej Przemysław Herman, Karolina Wojtulewicz, Bartosz Pawlina, Kamila Paczesna, Joanna Bochenek, Dorota Tomaszewska-Zaremba
Journal of Animal Science and Biotechnology
Karolina Haziak, Andrzej Przemysław Herman, Karolina Wojtulewicz, Bartosz Pawlina, Kamila Paczesna, Joanna Bochenek, Dorota Tomaszewska-Zaremba
Journal of Animal Science and Biotechnology
4.
Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide-Induced Systemic Inflammation
Andrzej P. Herman, Dorota Tomaszewska-Zaremba, Marta Kowalewska, Aleksandra Szczepkowska, Małgorzata Oleszkiewicz, Agata Krawczyńska, Maciej Wójcik, Hanna Antushevich, Janina Skipor
Mediators of Inflammation
Andrzej P. Herman, Dorota Tomaszewska-Zaremba, Marta Kowalewska, Aleksandra Szczepkowska, Małgorzata Oleszkiewicz, Agata Krawczyńska, Maciej Wójcik, Hanna Antushevich, Janina Skipor
Mediators of Inflammation
5.
Effect of Central Injection of Neostigmine on the Bacterial Endotoxin Induced Suppression of GnRH/LH Secretion in Ewes during the Follicular Phase of the Estrous Cycle
Andrzej Herman, Janina Skipor, Agata Krawczyńska, Joanna Bochenek, Karolina Wojtulewicz, Bartosz Pawlina, Hanna Antushevich, Anna Herman, Dorota Tomaszewska-Zaremba
International Journal of Molecular Sciences
Andrzej Herman, Janina Skipor, Agata Krawczyńska, Joanna Bochenek, Karolina Wojtulewicz, Bartosz Pawlina, Hanna Antushevich, Anna Herman, Dorota Tomaszewska-Zaremba
International Journal of Molecular Sciences
6.
Anandamide Influences Interleukin-1β Synthesis and IL-1 System Gene Expressions in the Ovine Hypothalamus during Endo-Toxin-Induced Inflammation
Monika Tomczyk, Dorota Tomaszewska-Zaremba, Joanna Bochenek, Anna Herman, Andrzej Herman
Animals
Monika Tomczyk, Dorota Tomaszewska-Zaremba, Joanna Bochenek, Anna Herman, Andrzej Herman
Animals
7.
Potential of dietary hemp and cannabinoids to modulate immune response to enhance health and performance in animals: opportunities and challenges
Faiz-ul Hassan, Chunjie Liu, Maryam Mehboob, Rana Bilal, Muhammad Arain, Faisal Siddique, Fengming Chen, Yuying Li, Jingmeng Zhang, Pengjun Shi, Biguang Lv, Qian Lin
Frontiers in Immunology
Faiz-ul Hassan, Chunjie Liu, Maryam Mehboob, Rana Bilal, Muhammad Arain, Faisal Siddique, Fengming Chen, Yuying Li, Jingmeng Zhang, Pengjun Shi, Biguang Lv, Qian Lin
Frontiers in Immunology
8.
Influence of Acute Inflammation on the Expression of Clock Genes in the Ovine Pars Tuberalis Under Different Photoperiodic Conditions
Karolina Wojtulewicz, Monika Tomczyk, Maciej Wójcik, Hanna Antushevich, Joanna Bochenek, Andrzej Przemysław Herman
International Journal of Molecular Sciences
Karolina Wojtulewicz, Monika Tomczyk, Maciej Wójcik, Hanna Antushevich, Joanna Bochenek, Andrzej Przemysław Herman
International Journal of Molecular Sciences
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| ISSN: | 1230-1388 |
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