The effectiveness of mineral mixtures balancing the mineral nutrition of cows in 8 chosen dairy farms using different winter feeding models, traditional (T) or modern (M), was evaluated. A positive influence of mixture A used in barns with the traditional feeding model was noted on milk yield (8% increase) and also on the level of some deficient minerals (Ca, P, K, Cu ≤ 0.05) in cows’ blood serum and on the potassium content in milk. Mixture (B), balancing mineral nutrition of cows from barns where the modern feeding model was used, did not significantly affect either milk yield or mineral level in blood plasma or milk in comparison with the commercial mixture.