SHORT COMMUNICATION
Magnesium increases calcium absorption mediated
by transcellular transport in small intestine of goats
and rats
1
Department of Animal Physiology, Graduate School of Agricultural Science, Tohoku University,
Amamiyamachi 1-1, Aoba-ku, Sendai 981-8555, Japan
Publication date: 2004-08-30
Corresponding author
T. Kozakai
Department of Animal Physiology, Graduate School of Agricultural Science, Tohoku University, Amamiyamachi 1-1, Aoba-ku, Sendai 981-8555, Japan
Department of Animal Physiology, Graduate School of Agricultural Science, Tohoku University, Amamiyamachi 1-1, Aoba-ku, Sendai 981-8555, Japan
J. Anim. Feed Sci. 2004;13(Suppl. 1):277-280
KEYWORDS
ABSTRACT
The effect of an increase in mucosal Mg concentration on Ca absorption mediated by
transcellular transport in the stripped epithelia of caprine ileum and rat jejunum was studied. In
Ussing chamber experiments, mucosal to serosal flux of Ca (Jms) at 60 mM MgCl2 was significantly
(P<0.05) greater than that of control (1.2 mM) in the absence of electrochemical gradient in goats
and rats. Furthermore, Mg-induced Jms was significantly decreased (P<0.05) after pre-incubation
with thapsigargin. It is concluded that Mg stimulates Ca absorption mediated by transcellular
transport, which contributed to the Ca store of endoplasmic reticulum.
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