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Suppl. 1/2004 vol. 13
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SHORT COMMUNICATION
Magnesium increases calcium absorption mediated by transcellular transport in small intestine of goats and rats
T. Kozakai 1
,
 
K. Katoh 1
,
 
Y. Obara 1
 
 
 
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Department of Animal Physiology, Graduate School of Agricultural Science, Tohoku University, Amamiyamachi 1-1, Aoba-ku, Sendai 981-8555, Japan
 
 
Publication date: 2004-08-30
 
 
Corresponding author
T. Kozakai   

Department of Animal Physiology, Graduate School of Agricultural Science, Tohoku University, Amamiyamachi 1-1, Aoba-ku, Sendai 981-8555, Japan
 
 
J. Anim. Feed Sci. 2004;13(Suppl. 1):277-280
DOI: https://doi.org/10.22358/jafs/73886/2004
 
 
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KEYWORDS
magnesium
calcium absorption
intestinal epithelia
transcellular pathway
 
ABSTRACT
The effect of an increase in mucosal Mg concentration on Ca absorption mediated by transcellular transport in the stripped epithelia of caprine ileum and rat jejunum was studied. In Ussing chamber experiments, mucosal to serosal flux of Ca (Jms) at 60 mM MgCl2 was significantly (P<0.05) greater than that of control (1.2 mM) in the absence of electrochemical gradient in goats and rats. Furthermore, Mg-induced Jms was significantly decreased (P<0.05) after pre-incubation with thapsigargin. It is concluded that Mg stimulates Ca absorption mediated by transcellular transport, which contributed to the Ca store of endoplasmic reticulum.
 
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