REVIEW PAPER
Polar overdominance – a putative molecular
mechanism and the new examples in mammals
More details
Hide details
1
National Research Institute of Animal Production,
Department of Animal Genetics and Breeding,
32-083 Balice, Poland
Publication date: 2009-01-23
Corresponding author
M. Oczkowicz
National Research Institute of Animal Production,
Department of Animal Genetics and Breeding,
32-083 Balice, Poland
J. Anim. Feed Sci. 2009;18(1):17-27
KEYWORDS
ABSTRACT
Polar overdominance is closely related to parental imprinting - a phenomenon where only one
(maternal or paternal) allele is expressed in the offspring. In contrast to gametic imprinting, polar
overdominance is not very well known and only few examples of this phenomenon have been reported
in mammals. One of them is the callipyge phenotype in sheep, which appears in the offspring
only when the mutated allele comes from the father and the wild allele comes from the mother. In review,
latest concepts on the molecular mechanism underlying the callipyge phenotype are presented
and the new examples in mammals are discussed.
CITATIONS (1):