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REVIEW PAPER
The contribution of vacuolated foetal-type enterocytes in the process of maturation of the small intestine in piglets. Invited review
1
John Paul II Catholic University of Lublin, Center for Interdisciplinary Research, Department of Biotechnology and Environmental Sciences, Laboratory of Confocal and Electron Microscopy, 20-708 Lublin, Poland
2
University of Life Sciences in Lublin, Faculty of Veterinary Medicine, Department of Animal Physiology, 20-950 Lublin, Poland
3
Warsaw University of Life Sciences – SGGW, Faculty of Veterinary Medicine,
Department of Large Animal Diseases with Clinic, 02-776 Warsaw, Poland
4
John Paul II Catholic University of Lublin, Center for Interdisciplinary Research,
Department of Biotechnology and Environmental Sciences, Laboratory of Biocontrol, Production and Application of Entomopathogenic Nematodes, 20-708 Lublin, Poland
5
University of Life Sciences in Lublin, Faculty of Veterinary Medicine, Institute of Biological Bases of Animal Diseases, Sub-Department of Parasitology and Invasive Diseases, 20-950 Lublin, Poland
Publication date: 2018-08-31
Corresponding author
T. Skrzypek
John Paul II Catholic University of Lublin, Center for Interdisciplinary Research, Department of Biotechnology and Environmental Sciences, Laboratory of Confocal and Electron Microscopy, 20-708 Lublin, Poland
John Paul II Catholic University of Lublin, Center for Interdisciplinary Research, Department of Biotechnology and Environmental Sciences, Laboratory of Confocal and Electron Microscopy, 20-708 Lublin, Poland
J. Anim. Feed Sci. 2018;27(3):187-201
KEYWORDS
foetal-type enterocytescolostrum uptakepostnatal developmentmucosa rebuildinglarge vacuolesgiant vacuoles
TOPICS
ABSTRACT
In neonates the vacuolated foetal-type enterocytes (VFE) play
a key role in the transport of intact colostral and milk proteins from the lumen
of the small intestine into the circulation and/or in the intracellular digestion of
intestinal nutrients. The absorption of intact colostral macromolecules (including
immunoglobulins, hormones and bioactive peptides) is important in the development
of the immune and digestive systems of newborn piglets. The digestion of
the intestinal content inside the VFE supports the luminal digestion of nutrients.
The presence of apical canalicular system, which produces both the transport
and the digestive vacuoles, is a key feature of VFE. The VFEs are gradually
replaced by adult-type enterocytes. VFEs disappear gradually from the proximal
part of the small intestine to the ileum. VFEs containing large (also referred to
as giant) transport vacuoles disappear within the first 2–3 days after birth. VFEs
containing digestive vacuoles are present for up to week 3 of life. In contrast,
VFEs of intrauterine growth retarded piglets show abnormalities in their development
of the apical area. The loss of VFEs is a good marker of the small intestine
epithelium maturation.
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Atlas of the Pig Gut
Tomasz Skrzypek, Karolina Ferenc, Zdzisław Gajewski, Romuald Zabielski
Tomasz Skrzypek, Karolina Ferenc, Zdzisław Gajewski, Romuald Zabielski
3.
ADSA Foundation Scholar Award: New frontiers in calf and heifer nutrition—From conception to puberty
Niekerk van, A.J. Fischer-Tlustos, J.N. Wilms, K.S. Hare, A.C. Welboren, A.J. Lopez, T.T. Yohe, L.R. Cangiano, L.N. Leal, M.A. Steele
Journal of Dairy Science
Niekerk van, A.J. Fischer-Tlustos, J.N. Wilms, K.S. Hare, A.C. Welboren, A.J. Lopez, T.T. Yohe, L.R. Cangiano, L.N. Leal, M.A. Steele
Journal of Dairy Science
4.
Early Life Antibiotics Influence In Vivo and In Vitro Mouse Intestinal Epithelium Maturation and Functioning
Tânia Garcia, Roest van, Jacqueline Vermeulen, Sander Meisner, Wouter Smit, Joana Silva, Pim Koelink, Jan Koster, William Faller, Manon Wildenberg, Elburg van, Vanesa Muncan, Ingrid Renes
Cellular and Molecular Gastroenterology and Hepatology
Tânia Garcia, Roest van, Jacqueline Vermeulen, Sander Meisner, Wouter Smit, Joana Silva, Pim Koelink, Jan Koster, William Faller, Manon Wildenberg, Elburg van, Vanesa Muncan, Ingrid Renes
Cellular and Molecular Gastroenterology and Hepatology
6.
Effects of colostrum management on transfer of passive immunity and the potential role of colostral bioactive components on neonatal calf development and metabolism
A.J. Fischer-Tlustos, A. Lopez, K.S. Hare, K.M. Wood, M.A. Steele, Gregory Penner
Canadian Journal of Animal Science
A.J. Fischer-Tlustos, A. Lopez, K.S. Hare, K.M. Wood, M.A. Steele, Gregory Penner
Canadian Journal of Animal Science
7.
Assessment of intestinal macromolecular absorption in young piglets to pave the way to oral vaccination: preliminary results
Brodie Deluco, Heather Wilson
Veterinary Research Communications
Brodie Deluco, Heather Wilson
Veterinary Research Communications
8.
The role of goblet cells and mucus in intestinal homeostasis
Jenny Gustafsson, Malin Johansson
Nature Reviews Gastroenterology & Hepatology
Jenny Gustafsson, Malin Johansson
Nature Reviews Gastroenterology & Hepatology
9.
Antenatal Ureaplasma infection induces ovine small intestinal goblet cell defects: a strong link with NEC pathology
Gorp van, Lange de, Matthias Hütten, Carmen López-Iglesias, Kimberly Massy, Lilian Kessels, Boris Kramer, de van, Brad Spiller, George Birchenough, Gemert van, Luc Zimmermann, Tim Wolfs
Tissue Barriers
Gorp van, Lange de, Matthias Hütten, Carmen López-Iglesias, Kimberly Massy, Lilian Kessels, Boris Kramer, de van, Brad Spiller, George Birchenough, Gemert van, Luc Zimmermann, Tim Wolfs
Tissue Barriers
10.
Pharmacokinetics of toltrazuril and its metabolite, toltrazuril sulfone, in suckling piglets following oral and intramuscular administrations
Ta‐Wei Yeh, Tirawat Rairat, Chao‐Ming Wang, Ching‐Fen Wu, Szu‐Wei Huang, Chi‐Chung Chou, Hung‐Chih Kuo
Journal of Veterinary Pharmacology and Therapeutics
Ta‐Wei Yeh, Tirawat Rairat, Chao‐Ming Wang, Ching‐Fen Wu, Szu‐Wei Huang, Chi‐Chung Chou, Hung‐Chih Kuo
Journal of Veterinary Pharmacology and Therapeutics
| ISSN: | 1230-1388 |
Assigning DOI numbers, introducing articles from supplements and recent publications to POL-index database, maintaining anti-plagiarism detection, electronic system to proceed manuscripts and webpage of the Journal with interactive pdf files, and language correction of manuscripts published in Journal of Animal and Feed Sciences are financed in the years 2018–2019 by the Ministry of Science and Higher Education from the funds for science popularization activities, Agreement No. 631/P-DUN/2018.
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