Three hundred and eighty-four day-old Ross broiler chicks were used in a completely randomized experimental design with 4×2 factorial arrangements using four rapeseed meal (RSM) levels with and without a multi-enzyme preparation. RSM levels included: A: control (without RSM); B: 5, 10 and 15%; C: 10, 15 and 20%; D: 15, 20 and 25% RSM in starter, grower and finisher periods, respectively. Body weight gain and feed conversion ratio in treatments B and C were similar to controls, but in treatment D, weight gain decreased and FCR increased (P<0.05). Feed intake of broilers was not affected by different levels of RSM (P>0.05). Enzyme supplementation had no significant effect (P>0.05) on growth performance but resulted in a significant increase in ileal digestibility of protein (P<0.05). Feeding high levels of RSM (Treatment D) significantly increased liver and gizzard weights and decreased abdominal fat (P<0.05).