REVIEW PAPER
The role of animal feeding trials for the nutritional
and safety assessment of feeds from genetically
modified plants – Present stage and future
challenges
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1
Institute of Animal Nutrition, Friedrich-Loeffler-Institute (FLI),
Federal Research Institute of Animal Health,
Bundesallee 50, D-38116 Braunschweig, Germany
2
Former Institute of Animal Sciences, ETH Zurich, ETH-Zentrum,
CH-8092 Zurich, Switzerland
Publication date: 2010-05-14
Corresponding author
G. Flachowsky
Institute of Animal Nutrition, Friedrich-Loeffler-Institute (FLI),
Federal Research Institute of Animal Health,
Bundesallee 50, D-38116 Braunschweig, Germany
J. Anim. Feed Sci. 2010;19(2):149-170
KEYWORDS
ABSTRACT
The world´s population is still growing up and asking for more and better food. High yielding
plants with low external inputs should be the main aim of plant breeding to meet the higher
demand for man and animal. Apart from traditional breeding plant biotechnology seems to have
a certain potential to contribute to this objective. Safety and nutritional studies with such modified
plants are the most important prerequisites for public acceptance of derived feed and food.
The first step for safety and nutritional assessment of modified plants is the compositional
analysis of potential food/feed and including the newly expressed proteins and other new
constituents and the comparison with conventional counterparts. In vitro studies and experiments
with laboratory animals are the next steps for assessments. Feeding studies with target animals are
of special concern for nutritional assessment and are considered in more detail in the present paper.
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